Silica Nanoparticles from Rice Husk Ash: A Green Catalyst for the One-Pot Three- Component Synthesis of BenzoSFuran Derivatives

摘要

Reaction of an isocyanide with an iminium ion intermediate, formed by reaction between an electronpoor 2-hydroxybenzaldehyde derivative and a secondary amine in the presence of silica nanoparticles proceeds smoothly at room temperature to afford benzo[b]furan derivatives in high yields.