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Improved Biphasic Pulsing Power Efficiency with Pt-Ir Coated Microelectrodes

机译:利用PT-IR涂层微电极提高了双相脉冲功率效率

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Neuromodulation devices such as deep brain stimulators (DBS), spinal cord stimulators (SCS) and cochlear implants (CIs) use electrodes in contact with tissue to deliver electrical pulses to targeted cells. In general, the neuromodulation industry has been evolving towards smaller, less invasive devices Improving power efficiency of these devices can reduce battery storage requirements. Neuromodulation devices can realize significant power savings if the impedance to charge transfer at the electrode-tissue interface can be reduced. High electrochemical impedance at the surface of stimulation microelectrodes results in larger polarization voltages. Decreasing this polarization voltage response can reduce power required to deliver the current pulse. One approach to doing this is to reduce the electrochemical impedance at the electrode surface. Previously we have reported on a novel electrochemically deposited 60:40% platinum-iridium (Pt-Ir) electrode material that lowered the electrode impedance by two orders of magnitude or more. This study compares power consumption of an electrochemically deposited Pt-Ir stimulating microelectrode to that of standard Pt-Ir probe microelectrode produced using conventional techniques. Both electrodes were tested using in-vitro in phosphate buffered saline (PBS) solution and in-vivo (live rat) models.
机译:神经调节装置,例如脑深部刺激器(DBS),脊髓刺激(SCS)和耳蜗植入(CI)的使用的电极与组织接触以提供电脉冲的靶细胞。一般地,所述神经调节行业一直在不断发展朝向提高这些设备的功率效率可降低电池的存储需求更小,更侵入性的装置。神经调节装置可实现显著的功率节省,如果能够降低阻抗以在电极 - 组织界面的电荷转移。在较大的极化电压刺激微电极的结果的表面高的电化学阻抗。减小该极化电压响应可以减少功率所需递送的电流脉冲。一种方法是这样做是为了减少电化学阻抗在电极表面处。先前我们已经报道上电化学沉积60的新颖:由数量级或更多的两个数量降低了电极的阻抗的40%的铂 - 铱(PT-IR)的电极材料。这项研究比较的电化学沉积的铂 - 铱刺激微电极到该标准的Pt-IR探针微电极的功率消耗使用常规技术制备。两个电极都使用体外在磷酸盐缓冲盐水(PBS)溶液和体内(活大鼠)模型中测试。

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