Improvement of Mass Transport at the Surface of an SPR Biosensor Applied in Microfluidics

摘要

The main objective of this work is to improve particle transport in a sensitive membrane microchannel in order to reduce the detection time of the biosensor. This requires analyzing the effects to improve the performance of the biosensor. Using numerical simulations, we studied the effect of the application of a magnetic field on the kinetic response of the biosensor. Thus the coupling of diffusion convection phenomenon with the adsorption and desorption reaction of the molecules on the Surface Resonance Biosensor Surface (SPR). These simulations are based on Navier Stokes equations, mass transport equations, chemical kinetics equations, and magnetostatics equations. The results found show an improvement in the fluid velocity and subsequently the diffusion and convection mass transport at the biosensor surface.