Preparation and Characterization of Shellac/Polyvinylpyrrolidone nanofiber as a Material for medical application

摘要

Nanofiber are defined as diameter less than 1 micron is under development for future medical application. The simple method was used to prepare a nonwoven in nanofiber of shellac (SHL) and polyvinylpyrrolidone (PVP) is electrospinning machine. The objective of the present study was to investigate the effect of electrospinning process on the physical properties. The SHL/PVP nanofiber was prepared by dissolving in various rations of SHL/PVP in ethanol solution. Properties of obtained SHL/PVP nanofibers were elucidated. The results demonstrated that nanofibers of SHL/PVP were easily formed after spinning with diameter ranging from a few nanometers to several micrometers. SHL and PVP blended fiber could be formed by the hydrogen bonds attributing to the change in physicochemical properties via FT-IR. This study indicated that a simple method to create nanofiber nonwovens of multiple dissimilar composite polymers providing an approach for controlling diameter size distribution independently from fiber formation. Hence, the knowledge gained should support the development of the product for medical application in near future.