Pattern Recognition of Fructus Cnidii Toxicity Study with Chemometrics Packages of R Software

摘要

Fructus Cnidii (FC) is a traditional Chinese medicine, but it has mild toxicity. To reveal mechanism of FC toxicity, we carried out metabonomics study. We exported mass data to be processed by chemometrics methods with R. Pattern recognition ability of different methods in different packages were evaluated. The result showed OPLS has powerful discriminative ability of pattern recognition. This work laid the foundation for selecting biomarkers of FC toxicity to reveal it's mechanism.