EXPLORING TRIPLET ENTROPY IN HIV SEQUENCES

摘要

The growing volume of available data deposited in GenBank and other public domain sites allows to make some sequence comparisons on a large scale. In this work we intend to analyze how entropy measures taken directly on sequences of HIV virus can be used to identify functionality differences. We analysed half million HIV sequences available at GenBank in order to indentify clusters of sequence organization. These sequences do not possess, in principle, other differences. The elements with higher GC also seem to have a largest organization, which may indicate a greater adaptive capacity. Such segregation appears in other elements and we will explore them in greater detail along the work.