TiO_2 nanotubes Modified with Polyelectrolyte Multilayers as a drug delivery and its release behavior

摘要

TiO_2 nanotube arrays (TNTs) were preparation on Ti influoride containing electrolytes via anodization. Poly(diallyldimethylammonium chloride (PDDA)alternately was assembled with poly(acrylic acid) (PAA) to modified TiO_2 nanotube. the modified TiO_2 nanotube loaded with alendronate, and its release properties were investigated. The samples were characterized by scanning electronic microscope (SEM), Fourier transform infrared (FT-IR). The results show that the loading rate and loading amount of alendronate were greatly influenced by electrostatic interaction. It suggested that the PDDA/PAA multilayer films had a potential application in modifying TNTs for drug delivery.