Inhibition of Free Radical and Neuroprotective Effect of Four Varieties of Ficus deltoidea

摘要

Oxidative stress and the implications have been highlighted in the pathogenesis of many neurodegenerative disorder of the brain including Alzheimer's disease. Nowadays, the interests in the protective role of several plants extracts are growing up. Plants antioxidants ability includes the inhibition of reactive oxygen species (ROS) overproduction and up-regulation of endogenous antioxidant defences. In this study, neuroblastoma cell line, SH-SY5Y was used to determine the neuroprotective effect of the leaves and figs of aqueous extract of four varieties of Ficus deltoidea namely var kunstleri, var angustifolia, var deltoidea, and var intermedia. The study showed the positive interaction between the inhibition of free radical with the neuroprotective effect against hydrogen peroxide (H2O2)-induced in SH-SY5Y cells.