A facile Synthesis of 4-aryl-3,4-Dihydropyrimidin-2(1H)-Ones in Iconic Liquids

摘要

4-aryl-3,4-dihydropyrimidin-2(lH)-ones were synthesized by using Biginelli reaction in iconic liguids. The simple method provoids the title compounds in 67-97% yields by the reaction of aromaic aldehydes with aectoacetrate and urea in the presence of iconic liquids as solvent and katalyst. This method was found to be efficient way for the synthesis of 4-aryl-3,4-dihydropyrimidin-2( 1 H)-ones.