Antioxidant activity of Acanthopanax senticosus extract and derivatives

摘要

Antioxidant activities of acetone and methanol extracts from leaves of Acanthopanax senticosus, one of traditional Chinese medicine consumed in the east-north region of China, were examined by a DPPH (1,1-Diphenyl-2-picrylhydrazyl) radical-scavenging assay and a β-carotene-linoleic acid test. In DPPH, the antioxidant activity of the acetone extracts, methanol extracts and derivative were superior to that of control with IC50 were 298.58, 360.16 and 142.21μg/mL, respectively. In the β-carotene-linoleic acid test, IC50 were 305.37, 400.39 and 156.69μg/mL. It was concluded that Acanthopanax senticosus and its derivatives might be a potential natural source of antioxidants.