Study on catalytic epoxidation of olefins in ketone-hydrogen peroxide system

摘要

Epoxides are important intermediates in organic synthesis, ketone-hydrogen peroxide was a clean and efficient catalytic oxidant for the epoxidation of olefins. Eleven ketone-hydrogen peroxide systems were used in the epoxidation of α-pinene to 2, 3-epoxypinane, acetone-hydrogen peroxide system gave the best yield and selectivity (91.8% and 97.5% in turn) among the eleven systems. Other two kinds of terpenes, three kinds of aromatic olefins, and three kinds of cycloolefins were oxidized under the acetone-hydrogen peroxide system with yields among 72.6% to 93.2%. For aromatic olefins and cycloolefins, the reactant with the electron-donating group gave a higher yield than those with the electron-withdrawing group.