Neuronal Patterns in the Cavity Wall of Lesions during Gait Cycle in a Rat Model of Brain Lesion Cavities

摘要

Oscillatory neural activity was reported to have various physiological roles in information processing of brain functions. It is now established that extracellular activity in the motor cortex encodes aspects of movement, involving planning and motor control. Oscillatory patterns have also been hypothesized to play a role in brain recovery and functional remapping. In this study, we measured neural activity from within the cavity wall of a motor cortex lesion, in a rat model, while the animals performed a skilled walking task. We aim at providing a possible framework of analysis, focused on revealing oscillatory patterns in the cavity wall and their correlation with motor deficits, by using a combination of spectral features, involving power spectra and coherence estimates in the beta and gamma frequency bands.