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Immunotherapy versus pharmacotherapy in Asthma

机译:免疫疗法与哮喘的药物治疗

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Asthma is a multi-factorial disease. Exercise, industrial and occupational agents, weather changes, viral infections, medications (e.g., aspirin), emotions, tobacco smoke and particulate matter may all trigger symptoms of asthma. Allergens are an important aspect to consider in the management of asthma, but allergens are not the only triggers that need to be controlled.In patients with asthma, there is a trend toward a lower correlation between asthma symptoms and allergy with increasing age. It is estimated that 90 percent of children with asthma have allergic disease; sensitivities include house-dust mites (50 a 60% of patients), animal dander (20 a 25%), pollens (20 a 30%) and molds (3 to 10%) Therefore, when possible, skin testing or RAST or Immunoblot testing is essential to define the allergic component of asthma, and these data should be used to direct appropriate environmental changes. Multiple studies have been performed stressing the importance of avoidance measures and techniques to accomplish avoidance in persons with asthma. However, even those measures asthmatic patients have not significant relief of their symptoms. The use of specific immunotherapy seems have at recent knowledge a better view in asthma treatment.
机译:哮喘是一种多因素疾病。运动,工业和职业药物,天气变化,病毒感染,药物(例如,阿司匹林),情绪,烟草烟雾和颗粒物质都可能引发哮喘的症状。过敏原是在哮喘管理中考虑的一个重要方面,但过敏原子不是需要控制的唯一触发器。哮喘患者,哮喘症状与年龄增加的哮喘症状与过敏之间的相关性趋势较低。据估计,90%的哮喘患儿具有过敏性疾病;敏感性包括房子 - 尘螨(50%患者的50%),动物剥皮(20 a 25%),花粉(20 a 30%)和模具(3至10%),因此,皮肤测试或rast或免疫印刷测试对于定义哮喘的过敏组分至关重要,这些数据应用于指示适当的环境变化。已经进行了多项研究,强调了避免措施和技术在哮喘人员中实现避免的重要性。然而,即使这些措施哮喘患者也没有显着缓解症状。最近的知识似乎在哮喘治疗方面似乎具有更好的观点。

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