A dynamic micro-CT scanner with a stationary mouse bed using a compact carbon nanotube field emission x-ray tube

摘要

In this paper we report the development of a high resolution dynamic micro-computed tomography (CT) scanner with a stationary mouse bed using a compact carbon nanotube (CNT) x-ray tube. The scanner comprises a rotating x-ray tube and detector pair and a stationary and a horizontally positioned small animal bed. The system is optimized for in vivo mouse cardiac imaging. Its performance is evaluated with CT scans of phantoms and free-breathing mice. The modulation transfer function (MTF) at 10% is 5 lp/mm. At single frame acquisition, mouse cardiac micro-CT at 20 msec temporal resolution has been demonstrated by prospectively gating the imaging acquisitions to both respiration and cardiac signals.