In humans and dogs, several degenerative disorders of the supraspinatus tendon have been identified, including rotator cuff tears, calcifying tendonitis or tendinosis (microtears), and tendinosis as a result of overuse. Degeneration of the supraspinatus tendon is thought to be a factor in the development of rotator cuff tears in humans. Good evidence indicates that overuse is likely an important factor in this disorder. At the cellular level, affected tendons contain discontinuous, disorganized fibers, and typically, no inflammation is detected. In chronic cases, a rapidly growing nodule develops that can impinge on the biceps brachii tendon and cause pain.
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