Development on ethanol production from xylose by recombinant Saccharomyces cerevisiae

摘要

Xylose is the second major fermentable sugar present in lignocellulosic hydrolysates, so its fermentation is essential for the economic conversion of lignocellulose to ethanol. However, the traditional ethanol production strain Saccharomyces cerevisiae does not naturally use xylose as a substrate. A number of different approaches have been used to engineer yeasts to reconstruct the gene background of S. cerevisiae in recent years. The recombinant strains showed better xylose-ferm entation quality by comparison with the natural strains. This review examines the research on S. cerevisiae strains that have been genetically modified or adapted to ferment xylose to ethanol from three aspects including construction of xylose transportation , xylose-metabolic pathway and inhibitor tolerance improvement of S. cerevisiae.