Investigation of Nano-Particle Metal Oxide Supports for the Oxidative Coupling of 4-Methylpyridine Over Palladium

摘要

Bypyridines are important due to their ability to coordinate to transition metal ions and form complexes with interesting electronic properties. For example, these organometallic complexes can be utilized in numerous catalyst systems. However, due to the difficulty of synthesizing bipyridines, they are prohibitively expensive for large scale processes, which limit their wide-range application. The oxidative coupling of 4-methylpyridine to 4,4'-dimethyl-2,2'-bipyridine over palladium is a one-step process in which the bipyridine is formed directly from the pyridine reactant via C-H activation and C-C coupling. The only by-products of this reaction are water and the terpyridine. No solvent or halogenated compounds are needed, which make this an environmentally friendly pathway to bipyridine compared with synthesis methods using halogenated precursors.