Development of a judgment method for functional damage of nerve cell PC12 associated with tension test

摘要

In this study, a new head injury criterion, which is evaluated by using the tension test, is proposed. In order to obtain the threshold value for brain's organ and tissue, the in vitro tension tests of cultured nerve cells were performed. PC12 cultured nerve cell was adopted to imitate the human's nerve cell. In the experiments, various strain were generated by micro manipulater. Relationships between the tensile strain and the damage of the higher-order function of the neuronal cell were obtained.