Preparation of DNA Hybrid Polyethersutfone Microspheres for Endocrine Disruptor Removal

摘要

In this paper, DNA hybrid polyethersulfone (PES) microspheres, including DNA-loaded porous particles and DNA-encapsulated hollow particles, are fabricated using a liquid-liquid phase separation method based on precipitation technique; the microspheres are then used for the removal of poisonous organic chemicals and endocrine disrupters. With the increase of the DNA amount incorporated into the spheres, the removal ratios increased both for the poisonous organic chemicals and endocrine disrupters. The particles without DNA also remove and accumulate poisonous organic chemicals due to the high porosity of the spheres. The results suggested that DNA hybrid PES particles could be prepared by a liquid-liquid phase separation method, and have potential to serve as a useful functional biomatetial for medical, engineering, and environmental application.