NONSPECIFIC DEFENCE MECHANISMS IN PIKEPERCH (SANDER LUCIOPERCA) GROWN IN AN INTENSIVE SYSTEM OF CULTURE AND IN NATURAL CONDITIONS

摘要

The defence mechanisms is a highly evolved system that functions to provide organisms with the ability to resist pathogenic agents, destroy neoplastic cells and reject nonself components. Defence mechanisms are characterised .by two pathways. The first is nonspecific cellular and humoral immune response: cellular mediated by phagocytes (monocytes/macrophages and granulocytes) and humoral presented by lysozyme, C-reactive protein, complement levels and inflammatory responses. The second is specific immune responses mediated by several activated lymphocytes which are directed and specific for an eliciting antigen. Nonspecific cellular and humoral defence mechanisms are a very important part of immunological mechanisms and perform a key role in the regulation of immune response. Several parameters of defence mechanisms have been used to study the influence of xenobiotics, diets and different system of culture on nonspecific cellular and humoral defence mechanisms, specific immune response with level of specific Ig and disease resistance in fish. The aim of this study was to examine the nonspecific cellular and humoral defence mechanisms of pikeperch (Sander luciopercd) grown in an intensive system of culture or in natural conditions.