Raman Spectroscopic Analysis of Ionisation Processes in Biological Systems

摘要

Raman spectroscopy was employed to spectroscopically fingerprint the range of amino acids, purines and pyramidines. Irradiation of these components by 10 Gray gamma rays shows that several of the amino acids and pyrimidines are particularly prone to molecular degradation. The spectroscopic signature of the degradation is utilised to identify the molecular origin of the degradation observed in the various biological macromolecules. Irradiation in solution compared to solid state is employed in an effort to differentiate between primary and secondary ionisation processes.