Gingivitis Prevention: Integration of Iron (II, III) Oxide Nanoparticles into Commercial Mouthwash

摘要

2010 Data from the Center for Disease Control and Prevention estimated that 64.7 million of American adults are victims of periodontitis, a dangerous and irreversible periodontal disease. The early form of periodontitis is gingivitis, a reversible, yet widespread disease that is commonly overlooked. Therefore, experimentation is taking place to incorporate nanoparticles into dental care. Metal oxide nanoparticles have outstanding antimicrobial abilities, but may cause cytotoxicity within the human body. The high number of periodontitis patients and the biomedical limitations of nanoparticles have led to the need for non-toxic antimicrobial substances that are safe to be used in dental care products. A solution to this need may be found in the incorporation of iron (II, III) oxide nanoparticle in commercial mouthwash.