Mechanism and Kinetics of Polymorphic Transportation： From Amorphous to Hydrate Crystal of Disodium Guanosine 5′-Monophosphate in Ethanol(PPT)

摘要

I. A typical solution-mediated transformation from amorphous to crystal appeared in 5'-GMPNa2 crystallization process. II. The determining step is nucleation of hydrate crystal. III. The results can be used to govern the control for an industrial process of a desired polymorphous structure。 The inline Raman is a key means for the study of transformation process, so later some inline Raman data should be added in this work to verify the XRD data.