The C1 Expression System – An industrial scale platform for enzymes and other proteins

摘要

The C1 Expression System, based on the Myceliophthora Thermophila fungus, a soil-borne saprophyte, is a robust and versatile platform for gene discovery, expression and the production of enzymes and other proteins. Mr. Brooks will discuss Dyadic’s commercial developments and progress toward producing cost-competitive enzyme and protein products for a variety of industries including biofuels, bio-based chemicals, biopharmaceuticals and industrial enzymes. Developed over the past two decades through UV-induced mutation and other bioengineering methods, C1 addresses the critical bottlenecks of protein discovery, development, scale-up and commercialization. The technology enables new product introduction with less time, cost and risk. Broad platform capabilities have been validated through 18 years of commercial-scale production (up to 150,000 liters) and 16 years of product sales and partnerships.