Improved Permeation Property of Polyethersulfone and Soybean Phosphatidylcholine Blend Ultrafiltration Membranes by Adjustment of Pore-Forming Agent

摘要

Polyethersulfone (PES) membrane has been widely used in protein separation and purification. However, in many cases, the nonspecific protein adsorption on the membrane surface and in the membrane pore due to the inherent hydrophobic characteristics of PES often causes significant membrane fouling and thus rapid decline of permeation flux. This exerts severe limitation for industrial applications. Many investigations have revealed that increasing membrane surface hydrophilicity could effectively reduce membrane fouling, therefore, incorporation of hydrophilic polymer through blending, coating, and surface grafting4 were subsequently developed to improve the protein-adsorption-resistance and permeation property of PES membrane.