8 Chitosan-Crosslinked Gels Prepared by a Simultaneously Occurring Reaction of Radiation-Induced Polymerization and Self-Bridging of Acrylic Acid in Aqueous solutions

摘要

Chitosan is one of the most interesting natural polymers, in addition to its biodegradability it shows wide biological propeties such as antifibrolastic and antimicrobial activities, which verify its biomedical application. Novel Acrylic acid/Chitosan hydrogel was prepared by means of gamma -irradiation as a clean source for initiation, and crosslinking. The nature of the AAc/CS gel and the effect of the presence of chitosan on the behavior of AAc were characterized. The effect of pH on the degree of swelling of different gels and time course swelling studies show the effect of presence of chitosan and its molecular weight on the swelling of the gels. DSC and TGA were used to study the effect of the presence of chitosan on the thermal behavior of PAAc.