Electroreductive Double Carbon-Carbon Bond Formation of Alkyl Methacrylates

摘要

Extensive studies have been concentrated on synthesis of 1,4-dicarbonyl compounds,especially 1,4-diketones,which are of much importance as the synthetic intermediates of many biologically active substrates and useful heterocyclic compounds such as pharmaceutical drugs,insecticides and perfume materials containing the ring systems of cyclopentenones,furans,pyrroles,and thiophenes.We have already reported electrochemical or Mg-promoted regioselective C-acylation of alpha,beta-unsaturated carbonyl compounds to give the corresponding C-acylated 1,4-dicarbonyl compounds.