Facile Synthesis of Useful Carboxylic Acids by Electrochemical Carboxylation

摘要

Electrochemical fixation of carbon dioxide is a useful and attractive method for efficient synthesis of various carboxylic acids.We previously reported that electrochemical carboxylation of alrylic and propargylic halides,vinyl bromides,vinyl triflates,and phenyl-substituted alkenes proceeded efficiently to give the corresponding carboxylic acids in high yields when a magnesium metal was used as a sacrificial anode.In this paper,we report facile synthesis of arenedicarboxylic acids and cyclic alpha-alkoxyl- or cyclic alpha-amino-alpha,beta-unsaturated carboxylic acids by electrochemical carboxylation of polyaromatic compounds and lactone or lactam enol triflates.