A novel tool based on ac-QCM transducers for improving antigens/antibodies interactions.

摘要

The detection of Ab/Ag interactions continues to be the subject of several research efforts by using various transducing techniques such as electrochemical,acoustic,optic transducers...In order to enhance these interactions a novel approach was tested by coupling ac-QCM(Quartz Crystal Microbalance),used under dynamic regime,and electrochemical impedances measurements on bioactive polymers.More precisely,the main objective of this work was to characterize the interaction between an antigen,human serum albumin(HSA)and an antibody(anti-HSA)immobilized inside polypyrrole films.