Xenotransplantation of cultured newborn pig thyroid tissue for the treatment of post-radioiodine hypothyroidism in rats

摘要

Persistent hypothyroidism resulting from radioiodine or X-rays irradiation of the thyroid gland requires an additional treatment with L-Thyroxine for a long period of time, and even for life [1]. Hormonal therapy using transplantation of thyroid tissue may deliver such patients from a pharmacotherapy [1-3]. Reports already exist on clinical use of autotransplantation of cryopreserved thyroid gland in patients with postoperative hypothyroidism [1-3]. However, all other forms of hypothyroidism exclude the possibility of autotransplantation of thyroid gland.