Synthesis and Characterization of pH-Responsive Poly(organophosphazene)Hydrogels

摘要

Water-soluble polyphosphazenes can be crosslinked either by gamma-radiation or by di- or tri-valent cations. The resultant materials imbibe or extrude water in response to changes in temperature, pH, or cations. These hydrogels offer the prospect of uses in responsive membranes, devices for the controlled delivery of drugs, enzyme immobilization and mediation media, and tissues engineering.