It was noticed that the effect of wall deformability on internal flows is remarkably augmented due to altered gravity. For the realistic carotid artery model, the wall distensibility has a quantitative influence on unsteady flow patterns and temporal wall shear stress distribution. In addition, not only the effect of altered gravity on cerebral circulation but also the mechanism of collateral circulation in autoregulation was demonstrated through the idealized CoW configuration. The solution procedure based on parallel computation adopted in this study has shown its capability that can model the multi-scale hemodynamics for the various types of the human circulatory system.
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