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ANALYSIS OF FLOW AND WALL SHEAR STRESS IN CURVATURE INDUCED DORSAL ANEURYSMS: EFFECT OF ARTERIAL CURVATURE

机译:曲率诱导背动脉瘤流动和壁剪切应力分析:动脉曲率的影响

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Intracranial aneurysms are abnormal enlargement in the walls of cerebral arteries. The rupture of aneurysms is the leading cause of subarachnoid hemorrhage (SAH), with a high mortality and morbidity rate. A majority of saccular cerebral aneurysms occur at sites of arterial bifurcations. However, a good percentage of aneurysms are curvature induced and are found along the cavernous arterial segment. The occurrence of such non branching aneurysms, clinically called dorsal aneurysms, can be related to the increased wall shear stress at the curved arteries. The rupture of aneurysms usually occurs at the dome region, which is subjected to reduced wall shear stress (wss) owing to low re-circulating flow. Hence it is important to understand the impact of arterial curvature on the WSS distribution along the dome of aneurysms. Previously, studies have not taken into account the aspect of low WSS along the dome region. In the present 3-d computational fluid dynamic approach, we investigate the impact of varying arterial curvature on spherical dorsal aneurysms. The primary velocity patterns, the WSS distribution along the dome of the aneurysm and the area of increased WSS have been quantified for steady flow conditions.
机译:颅内动脉瘤是脑动脉壁的异常扩大。动脉瘤破裂是蛛网膜下腔出血(SAH)的主要原因,具有高死亡率和发病率。大多数椎弓带动脉瘤发生在动脉分叉的部位。然而,良好的动脉瘤是曲率诱导的并且沿着海绵状动脉段发现。这种非分支动脉瘤的发生临床称为背部动脉瘤可以与弯曲动脉的增加的壁剪切应力有关。动脉瘤的破裂通常发生在圆顶区,由于低再循环流动,在圆顶区域处经受降低的壁剪切应力(WSS)。因此,重要的是要了解动脉曲率对动脉瘤圆顶的影响。以前,没有考虑到圆顶区域的低WSS的研究。在本发明的3-D计算流体动态方法中,我们研究了不同动脉曲率对球形背动脉瘤的影响。沿着动脉瘤的圆顶和增加的WSS面积的主要速度模式已经被定量为稳定的流动条件。

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