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The Research Progress of Targeted Drug Delivery Systems

机译:靶向药物递送系统的研究进展

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摘要

Targeted drug delivery system (DDS) means to selectively transport drugs to targeted tissues, organs, and cells through a variety of drugs carrier. It is usually designed to improve the pharmacological and therapeutic properties of conventional drugs and to overcome problems such as limited solubility, drug aggregation, poor bio distribution and lack of selectivity, controlling drug release carrier and to reduce normal tissue damage. With the characteristics of nontoxic and biodegradable, it can increase the retention of drug in lesion site and the permeability, improve the concentration of the drug in lesion site.at present, there are some kinds of DDS using at test phase, such as slow controlled release drug delivery system, targeted drug delivery systems, transdermal drug delivery system, adhesion dosing system and so on. This paper makes a review for DDS.
机译:靶向药物递送系统(DDS)意味着通过各种药物载体选择性地将药物转运至靶向组织,器官和细胞。通常旨在改善常规药物的药理学和治疗性能,并克服有限的溶解度,药物聚集,生物分布,缺乏选择性,控制药物释放载体等问题,并降低正常组织损伤。随着无毒和可生物降解的特点,它可以增加药物在病变部位中的药物保留和渗透性,提高病变位点中药物的浓度。存在,存在某些类型的DDS,如缓慢控制释放药物递送系统,靶向药物递送系统,透皮药物递送系统,粘附剂量系统等。本文对DD进行了审查。

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