Telemonitoring Protocol for Prevention and Comorbidity Screening, in Paediatric Patients with Cystic Fibrosis and/or Diabetes, by HVR index

摘要

This pilot project is one of the first applications of Telemedicine solution (Telemonitoring) for comorbidity and translational study. A total of 20 patients with Diabetes and/or Cystic Fibrosis were enrolled to a telemedical intervention and assigned to different Groups. The patients, who enrolled voluntarily, were as follows: 5 with consecutive Typel Diabetes Mellitus and assigned to Group 1; 5 with Cystic Fibrosis already under Telemonitorig protocol and assigned to Group 2; 5 with consecutive Type 1 Diabetes Mellitus and Cystic Fibrosis already followed at Bambino Gesu Children's Hospital, Unit of Endocrinology and Diabetes and by Telemedicine group of Cystic Fibrosis Unit and assigned to Group 3; and 5 voluntary without disease assigned to Group 4 (Control group). The Aim of this study was to analyze possible variation of Heart Rate Variability, depending on the glycaemia value or Forced Expiratory Volume in 1 second in adolescent and adult patients with diabetes and/or Cystic Fibrosis by telemedicine protocol and analyze the correlation between compliance and patients technology background. In the first four months of Telemonitoring, we received 855 glycaemia transmissions and 378 spirometry test transmissions. We show a good compliance trend, especially in the patients with technology background. For the patients or patient family members without technology background, we offered telephonic assistance to verify the home procedures, and to store and download the data. Preliminary analysis of data showed no overall significant differences in Heart Rate Variability parameters among the three groups. More months of observation are needed to show possible correlation between Forced Expiratory Volume in 1 second, glycaemia value and Health Rate Variability. Various Telemonitorig solutions could be important tools for new international comorbidity research, but an easy methodology to share the data from Home to Hospital has to be taken into consideration when planning a Telemedicine protocol assistance.