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Biomedical Entities Impact on Rating Prediction for Psychiatric Drugs

机译:生物医学实体对精神病药物评级预测的影响

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There is a growing body of research on biomedical information extraction on social media texts, patient narratives, and scientific abstracts. Relatively less research has focused on the relationship between medical concepts mentioned in a given user review and patient satisfaction. In this work, we investigate the effect of health-related entities such as adverse drug reactions and drug indications on rating prediction. We present a method based on a supervised regression approach leveraging medical concepts of different types and their mechanisms. The experiments on a collection of reviews demonstrate that features based on biomedical entities mentioned in reviews result in performance gains of up to 8% in mean squared error. Moreover, we compute feature importance in the regression models and find that the most important features for predicting patients' negative attitudes are adverse drug reactions associated with functional problems.
机译:社交媒体文本,患者叙述和科学摘要的生物医学信息提取有一种越来越多的研究。相对较少的研究专注于给定用户评论和患者满意度所提到的医学概念之间的关系。在这项工作中,我们研究了与额定预测的不良药物反应和药物指示等健康相关实体的影响。我们提出了一种基于监督回归方法的方法,利用不同类型的医疗概念及其机制。关于一系列评论的实验表明,基于评论中提到的生物医学实体的特征导致均方方错误的性能增益高达8%。此外,我们在回归模型中计算特征重要性,并发现预测患者的负态度最重要的特征是与功能问题相关的不利药物反应。

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