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Biomedical Entities Impact on Rating Prediction for Psychiatric Drugs

机译:生物医学实体对精神药物评级预测的影响

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There is a growing body of research on biomedical information extraction on social media texts, patient narratives, and scientific abstracts. Relatively less research has focused on the relationship between medical concepts mentioned in a given user review and patient satisfaction. In this work, we investigate the effect of health-related entities such as adverse drug reactions and drug indications on rating prediction. We present a method based on a supervised regression approach leveraging medical concepts of different types and their mechanisms. The experiments on a collection of reviews demonstrate that features based on biomedical entities mentioned in reviews result in performance gains of up to 8% in mean squared error. Moreover, we compute feature importance in the regression models and find that the most important features for predicting patients' negative attitudes are adverse drug reactions associated with functional problems.
机译:关于社交媒体文本,患者叙事和科学文摘中生物医学信息提取的研究越来越多。相对较少的研究集中在给定用户评论中提到的医学概念与患者满意度之间的关系。在这项工作中,我们调查了与健康相关的实体(例如药物不良反应和药物适应症)对等级预测的影响。我们提出了一种基于监督回归方法的方法,该方法利用了不同类型的医学概念及其机制。对一组评论进行的实验表明,基于评论中提到的生物医学实体的功能可以使平均平方误差的性能提升高达8%。此外,我们在回归模型中计算特征重要性,发现预测患者负面态度的最重要特征是与功能问题相关的药物不良反应。

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