The application of an incorporated rate-equilibrium model for the production of Pyrethroid compound process

摘要

Multiphase reacting system has broad range of application area including the manufacture of petroleum-based products, the production of chemicals, pharmaceuticals, and agro-bio products. In these systems, multiple phases are created by the immiscibility between co-exist solvents or separated by permeable membrane. The reactants and catalysts (including also biocatalysts and enzymes) can exist in different liquid phases, allowing novel synthesis paths as well as higher reaction rate and yield. Modelling of this system could offer an efficient way to help analysis and development; however, phenomena related to this system include partitions and diffusions of each chemical species between phases, dissociation of inorganic salt in aqueous phase, and reactions must be included. The objective of this work is to develop a mathematical model of the pyrethroid production process. The pyrethroid-class compound is a man-made organic compound used as insecticide. Pyrethroid is produced by reaction of cyclic aldehyde, organic acid, and inorganic salt in a liquid-liquid biphasic aqueous-organic system [1]. In this work, the reactor model was developed, parameters identified and tested against measured data. The result of the current model could competently predict Pyrethroid-class production rate.