Process Analytical Technology (PAT) includes all tools that can be used for analysing and controlling manufacturing through timely measurements (i.e., during processing) of critical quality and performance attributes of raw and in-process materials and processes with the goal of ensuring final product quality. The aim of the presentation is to show practical examples of the implementation of PAT to increase process understanding and efficiency on an industrial scale. The tools for process understanding and control are mainly based on multivariate data acquisition and analysis methods, and modern spectroscopic process analysers. These tools provide a scientific risk-based approach to justify how real time quality assurance may be equivalent to, or better than, laboratory-based testing on collected samples.
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