A Degradable Chitosan-graft-poly(ε-Caprolactone) Copolymeric Biomaterial Supports the Growth of Wharton's Jelly Mesenchymal Stem Cells for Soft Tissue Engineering

摘要

The present work shows the successful development of graft copolymeric discs, which demonstrate a strong cell adhesion and growth of WJ MSCs, together with mechanical properties similar to those of soft tissues. These results establish the basis for the potential use of this cell-material combination in soft tissue regeneration. Ongoing investigations on the differentiation of WJ MSCs may support this hypothesis.