Changing diagnostic strategies of mediastinal and hilar lymphadenopathies: EBUS-TBNA diagnosing benign lesions.

摘要

Here we report the results of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) use in 181 patients with mediastinal lymphadeno-pathy. EBUS-TBNA was applied to 58 female and 123 male (mean age 64,2 years and 24,4- 91,5 yrs range). Cytological exams were performed to all formalin fixed paraffin-embedded cell block and smear preparations obtained by biopsying lymph nodes from 2l, 2r, 4r, 4l, 7, 10r, 10l and 11l regions. Benign lesions were verified in 48% of cases whereas sarcoidosis in 35, caseating granulomas in 4 and cystic lesion in one. 44 patient cytograms showed nonspecific reactive lymphadenopathy and majority, 52% of the cohort revealed different malignant mediastinal processes. No complications were observed. EBUS-TBNA as the strategic first choice technology could be applied as a minimally invasive diagnostic approach to either in benign or malignant mediastinal and hilar lymphadenopathies. High specificity and accuracy can be ensured in diagnosing different benign lesions incl. sarcoidosis with safe and cost-effective way.