Comprehensive and Quantitative Lipidome Profiling of Colorectal Adenocarcinoma Cell Lines and Their Secreted Exosomes

机译：结肠直肠腺癌细胞系的综合和定量脂质谱分析及其分泌的外泌体

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Significant changes in the compositions of multiple lipid sub-classes observed between the primary cancer and metastatic cancer cell lines and their secreted exosomes. A large increase in PE, PS, SM overall % lipid ion abundance was observed in the exosome extracts compared to their respective cellular extracts. Greater than 1500 lipid species were identified overall.

机译：在原发性癌症和转移性癌细胞系之间观察到的多种脂质亚类组合物的显着变化及其分泌的外来体。与其各自的细胞提取物相比，PE，PS，PS，SM总％％脂质离子丰度观察到外部提取物。总体上鉴定出大于1500种脂质物种。

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《American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics》|2013年||共1页
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Cassie J. Fhaner; Hong Ji; Richard J. Simpson; Gavin E. Reid;
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中图分类 TB994.5-53;
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3. Exosomes secreted from human colorectal cancer cell lines contain mRNAs, microRNAs and natural antisense RNAs, that can transfer into the human hepatoma HepG2 and lung cancer A549 cell lines [J] . ChibaM., KimuraM., AsariS. Oncology reports . 2012,第5期

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4. Comprehensive and Quantitative Lipidome Profiling of Colorectal Adenocarcinoma Cell Lines and Their Secreted Exosomes [C] . Cassie J. Fhaner, Hong Ji, Richard J. Simpson, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2013

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5. Mass spectrometry strategies for comprehensive lipidome analysis of colorectal cancer cells and their secreted exosomes. [D] . Fhaner, Cassie J. 2014

机译：用于大肠癌细胞及其分泌的外泌体的全面脂质组分析的质谱策略。
6. Rapid and Comprehensive ‘Shotgun’ Lipidome Profiling of Colorectal Cancer Cell Derived Exosomes [O] . Todd A. Lydic, Steven Townsend, Christopher G. Adda, -1

机译：大肠癌细胞衍生外泌体的快速全面的 Shotgun脂质组分析
7. Rapid and comprehensive ‘shotgun’ lipidome profiling of colorectal cancer cell derived exosomes [O] . Todd A. Lydic, Steven Townsend, Christopher G. Adda, 2015

机译：快速和全面的“霰弹枪”脂质组的结肠直肠癌细胞衍生出外泌体

Comprehensive and Quantitative Lipidome Profiling of Colorectal Adenocarcinoma Cell Lines and Their Secreted Exosomes

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