Involvement of Peptide Size, Residue Position, Neighbor Amino Acid, and Side Chain on Macrocyclization of b_n (n = 5 to 7) ions

摘要

1. b_6 and b_7 ions have higher tendency towards macrocyclization when compared to b_5 ions. 2. Neighboring amino acid influences the selective opening of the macrocyclic b_6 ion. 3. No preferential cleavage order can be specified based on the nature of amino acid side chain. 4. W, K, and M were observed to be more favored eliminations from the macrocyclic b_6 and b_7 ions compared to the b_5 ions.