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A stabilized pharmaceutical formulation comprising a growth hormone, a peptide consisting of at least one basic amino acid residue and at least one acidic amino acid residue

机译:稳定的药物制剂,其包含生长激素,由至少一个碱性氨基酸残基和至少一个酸性氨基酸残基组成的肽

摘要

Pharmaceutical preparations comprising a growth hormone and a peptide consisting of at least one basic amino acid residue and at least one acidic amino acid residue as an additive or buffer substance exhibit very high stability against deamidation, oxidation and degradation of peptide bonds. The stability of this product allows its storage and transport in the form of lyophilized or reconstituted preparations in lyophilized or ambient temperature.
机译:包含生长激素和由至少一个碱性氨基酸残基和至少一个酸性氨基酸残基组成的肽作为添加剂或缓冲物质的药物制剂表现出非常高的抗肽键脱酰胺,氧化和降解的稳定性。该产品的稳定性使其可以在冻干或环境温度下以冻干或重构制剂的形式存储和运输。

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