Thermal Desorption Electrospray Ionizatin Mass Spectrometry for Efficiently Characterizing Small Chemical Compounds in Liquids and Solids

摘要

In this study, we demonstrated the effectiveness of combination of thermal desorption and electrospray ionization (TD-ESI) for a wide range of applications. Since the total analytical time of this approach for one sample is only a few seconds, it provides the capacity of screening a large number of the samples for rapid, real-time, in-suit and as well as high-throughput analysis. The technique with features of ambient ionization mass spectrometry shows the capability for a wide range of applications, in particular, environmental monitoring, food safety, drug abuse and homeland security.