Determination of Oligomeric Proanthocyanidins (OPCs) from Tamarindus indica Seed Coat (of Indian origin) using LC/MS/MS

摘要

The MS and MS results obtained from LC/MS/MS triple quadrupole system, helped in confirming the presence OPCs in Tamarindus indica seed coat even in the absence of standards. In antimicrobial sensitivity testing, the aqueous extract showed inhibition to the growth of Gram positive organisms whereas Gram negative organisms were unaffected. This indicates a narrow spectrum antimicrobial activity confined to Gram positive bacteria. The crude aqueous extract showed higher zone of inhibition than the final OPCs aqueous extract. Therefore, one may also conclude that in addition to OPCs, there is a synergistic action of other components that aid in antimicrobial activity exhibited by Tamarindus indica seed coat.