HDX-Mass Spectrometry Study of Amyloid beta (A(beta) 1-42) Peptide Oligomerization

机译：淀粉样蛋白β（A（β）1-42）肽寡聚化的HDX - 质谱研究

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Several diseases involve the amyloid deposition of proteins and peptides. The A(beta) peptide is implicated in Alzheimer's disease. There are several forms of A(beta) peptide, of which A(beta)1-42 is the most neurotoxic and diseaserelated.

机译：几种疾病涉及蛋白质和肽的淀粉样蛋白沉积。 A（β）肽涉及阿尔茨海默病。存在几种形式的（β）肽，其中a（β）1-42是最神经毒性和脱落。

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《American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics》|2011年||共1页
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Ying Zhang; Liviu L. Mirica; Michael L. Gross;
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1. Intravenous anesthetic diazepam does not induce amyloid-beta peptide oligomerization but diazepam co-administered with halothane oligomerizes amyloid-beta peptide: an NMR study. [J] . Mandal PK, Simplaceanu V, Fodale V Journal of Alzheimer's disease: JAD . 2010,第1期

机译：一项NMR研究表明，静脉麻醉药地西epa不会诱导淀粉样β肽寡聚，但与氟烷共同使用的地西epa会使淀粉样β肽低聚。
2. Nitration of amyloid-beta peptide (1-42) as a protective mechanism for the amyloid-beta peptide (1-42) against copper ion toxicity [J] . Zhao Jie, Gao Wanxia, Yang Zhen, Journal of Inorganic Biochemistry: An Interdisciplinary Journal . 2019,第期

机译：淀粉样蛋白β肽（1-42）的硝化作为淀粉样蛋白β肽（1-42）对铜离子毒性的保护机制
3. Reference measurement procedure for CSF amyloid beta (A beta)(1-42) and the CSF A beta(1-42)/A beta(1-40) ratio - a cross-validation study against amyloid PET [J] . Pannee Josef, Portelius Erik, Minthon Lennart, Journal of Neurochemistry: Offical Journal of the International Society for Neurochemistry . 2016,第4期

机译：CSF淀粉样蛋白β（A beta）（1-42）和CSF A beta（1-42）/ A beta（1-40）比率的参考测量程序-针对淀粉样蛋白PET的交叉验证研究
4. HDX-Mass Spectrometry Study of Amyloid beta (A(beta) 1-42) Peptide Oligomerization [C] . Ying Zhang, Liviu L. Mirica, Michael L. Gross American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2011

机译：淀粉样蛋白β（A（β）1-42）肽寡聚化的HDX - 质谱研究
5. Amyloid beta-peptide (1-42)-mediated oxidative stress and neurotoxicity: I. The role of methionine 35. II. Proteomic identification of specifically oxidized proteins in models of Alzheimer's disease. [D] . Boyd-Kimball, Debra Lynn. 2004

机译：淀粉样β-肽（1-42）介导的氧化应激和神经毒性：I.蛋氨酸的作用35. II。蛋白质组学鉴定阿尔茨海默病模型中特定氧化的蛋白质。
6. Solubilization of beta-amyloid-(1-42)-peptide: reversing the beta-sheet conformation induced by aluminum with silicates. [O] . G D Fasman, A Perczel, C D Moore 1995

机译：β-淀粉样蛋白-（1-42）-肽的增溶作用：逆转铝与硅酸盐诱导的β-折叠构象。
7. Nasal mucosal inhalation of amyloid-beta peptide 3-10 defective adenovirus attenuates cytotoxicity induced by beta-amyloid (1-42) [O] . Yunpeng Cao, Tongzi Jiang, Wanshu Guo, 2014

机译：蛋白粘膜吸入淀粉样蛋白β肽3-10缺陷腺病毒衰减β-淀粉样蛋白（1-42）诱导的细胞毒性

HDX-Mass Spectrometry Study of Amyloid beta (A(beta) 1-42) Peptide Oligomerization

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