A Sensitive and Rugged Normal Phase LC/MS/MS Method for Quantitation of Ribavirin in Human Plasma

机译：用于定量人血浆中利巴韦林的敏感和粗糙的正常相LC / MS / MS方法

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Removal of phospholipids allowed for development and validation of a sensitive, rugged, and reliable high-throughput assay for the determination of ribavirin in human plasma. This method has been validated with a ribavirin range of 5.00 to 5000 ng/mL. The assay is suitable for the analysis of clinical study samples as demonstrated by its specificity, precision, accuracy, recovery, and stability characteristics.

机译：除去磷脂允许的开发和验证敏感，粗糙和可靠的高通量测定，用于测定人血浆中利巴韦林。该方法已被验证，利巴韦林范围为5.00至5000ng / ml。该测定适用于通过其特异性，精度，精度，恢复和稳定性特征所证明的临床研究样本。

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《American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics》|2010年||共1页
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James Creegan; Marking Peay; Tianyi Zhang; Bruce Hidy; Rand Jenkins;
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中图分类 TB994.5-53;
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A Sensitive and Rugged Normal Phase LC/MS/MS Method for Quantitation of Ribavirin in Human Plasma

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