The Extraction and Analysis of siRNA from Rat Plasma using Mixed Mode SPE and HPLC-MS/MS

机译：使用混合模式SPE和HPLC-MS / MS从大鼠等离子体中的siRNA提取和分析

获取原文

页面导航

摘要
著录项
相似文献
相关主题

摘要

A method was successfully developed for the bioanalysis of this particular siRNA/ addressing the analytical challenges with a novel combination of strategies. This method presents itself as a generic approach for the bioanalysis of siRNA molecules, offering a starting point for method development, should bioanalytical support be required for similar molecules in the future.

机译：成功开发了这种特定siRNA的生物分析的方法/通过新的策略组合解决分析挑战。该方法本身呈现为SiRNA分子生物分析的通用方法，提供方法开发的起始点，是否应该在未来的类似分子所需的生物分析支持。

著录项

来源
《American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics》|2010年||共1页
会议地点
作者
Rob Wheller;
展开▼
作者单位

展开▼
会议组织
原文格式 PDF
正文语种
中图分类 TB994.5-53;
关键词

相似文献

外文文献
中文文献
专利

1. Sensitive and Rapid Quantification of Felodipine by High-performance Liquid Chromatography-tandem Mass Spectrometry(HPLC-MS/MS) and Its Pharmacokinetics in Healthy Chinese Volunteers [J] . 高等学校化学研究（英文版） . 2006,第004期
2. Sensitive and Rapid Quantification of Felodipine by High-performance Liquid Chromatography-tandem Mass Spectrometry（HPLC-MS/MS） and Its Pharmacokinetics in Healthy Chinese Volunteers [J] . LI, Yan-yan, YIN, 高等学校化学研究：英文版 . 2006,第004期
3. HPLC-MS/MS analysis of peramivir in rat plasma: Elimination of matrix effect using the phospholipid-removal solid-phase extraction method [J] . Lei Mingdao, Gan Wei, Sun Yongbing Biomedical Chromatography: An International Journal Devoted to Research in Chromatographic Methodologies and Their Applications in the Biosciences . 2018,第3期

机译：大鼠血浆中Peramivir的HPLC-MS / MS分析：消除使用磷脂去除固相提取方法的基质效应
4. Determination of S-propargyl-cysteine in rat plasma by mixed-mode reversed-phase and cation-exchange HPLC-MS/MS method and its application to pharmacokinetic studies. [J] . Zheng Y, Liu H, Ma G, Journal of Pharmaceutical and Biomedical Analysis: An International Journal on All Drug-Related Topics in Pharmaceutical, Biomedical and Clinical Analysis . 2011,第5期

机译：混合模式反相阳离子交换HPLC-MS / MS法测定大鼠血浆中的炔丙基半胱氨酸及其在药代动力学研究中的应用。
5. Rapid mixed mode solid phase extraction method for the determination of acrylamide in roasted coffee by HPLC-MS/MS [J] . Renzo Bortolomeazzi, Marina Munari, Monica Anese, Food Chemistry . 2012,第4期

机译：HPLC-MS / MS快速混合模式固相萃取法测定焙炒咖啡中的丙烯酰胺
6. The Extraction and Analysis of siRNA from Rat Plasma using Mixed Mode SPE and HPLC-MS/MS [C] . Rob Wheller American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2010

机译：使用混合模式SPE和HPLC-MS / MS从大鼠等离子体中的siRNA提取和分析
7. Study of Sequential Accelerated Solvent Extraction of Different Depths of Oak Tank Staves, Affected by Three Different Heat Sources, Analyzed by Gas Chromatography-Mass Spectrometry and Correlations to Sensory Descriptive Analysis of Their Model Wine Extractions. [D] . Llodra, David. 2013

机译：气相色谱-质谱联用分析了三种不同热源对不同深度橡木桶壁深度的顺序加速溶剂萃取及其与模型提取酒的感官描述相关性的研究。
8. Simultaneous Determination of Five Alkaloids by HPLC-MS/MS Combined With Micro-SPE in Rat Plasma and Its Application to Pharmacokinetics After Oral Administration of Lotus Leaf Extract [O] . Shuhan Zou, Yuanyuan Ge, Xuanhao Chen, 2019

机译：HPLC-MS / MS与大鼠血浆中的微型血管和荷叶提取物口服施用后的微型血管和药代动力学的同时测定五种生物碱
9. HPLC-MS analysis of Schisandra lignans and their metabolites in Caco-2 cell monolayer and rat everted gut sac models and in rat plasma [O] . Jia-ming Yang, Siu-po P. IP, Hok-keung J. Yeung, 2011

机译：五味子木脂素及其代谢产物在Caco-2细胞单层和大鼠外翻肠囊模型及大鼠血浆中的HpLC-ms分析

The Extraction and Analysis of siRNA from Rat Plasma using Mixed Mode SPE and HPLC-MS/MS

摘要

著录项

相似文献

相关主题

期刊订阅