Characterization of PET Radiotracers Through LC-MS/MS Measurement of the Radiotracer and Accompanying ~(13)CCarrier

机译：通过LC-MS / MS测量的抗毒反射器和伴随的宠物放射体制物的表征，并伴随〜（13）C载体

获取原文

页面导航

摘要
著录项
相似文献
相关主题

摘要

Mass-detection of very low concentrations of ~(11)C and ~(18)F species contained in excess carrier was achieved. Mass measurement alone of labeled and unlabeled species gave accurate measures of the specific activities of radiotracers. LC-MS/MS detection of radiotracer and accompanying [~(13)C]carrier can be a definitive method for the characterization of ~(11)C- and ~(18)F-labeled PET radiotracers, and also for verifying the accuracy of radio-HPLC measurements of radiotracer specific radioactivity.

机译：达到过量载体中含有的非常低浓度〜（11）C和〜（18）F物种的质量检测。单独标有标记和未标记物种的质量测量具有准确的放射性机构的特定活动的准确度。 rc-ms / ms检测辐射反射液和伴随[〜（13）c]载体可以是表征〜（11）C-和〜（18）F标记的宠物放射酸酯，以及用于验证精度的明确方法放射性机构特异性放射性的无线电HPLC测量。

著录项

来源
《American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics》|2010年||共1页
会议地点
作者
Umesha Shetty; Cheryl Morse; Yi Zhang; Victor Pike;
展开▼
作者单位

展开▼
会议组织
原文格式 PDF
正文语种
中图分类 TB994.5-53;
关键词

相似文献

外文文献
中文文献
专利

1. Characterization of fast-decaying PET radiotracers solely through LC-MS/MS of constituent radioactive and carrier isotopologues [J] . H Umesha Shetty, Cheryl L Morse, Yi Zhang, EJNMMI Research . 2013,第1期

机译：仅通过LC-MS / MS组成的放射性同位素和载体同位素同位素对快速衰减的PET示踪剂进行表征
2. LC-MS supported investigations on the metabolism of (+)-[F-18]flubatine, a radiotracer for imaging of alpha 4 beta 2 nicotinic acetylcholine receptors by PET [J] . Ludwig Friedrich-Alexander, Fischer Steffen, Smits Rene, Journal of Labelled Compounds and Radiopharmaceuticals . 2015,第Suppla期

机译：LC-MS支持对（+）-[F-18]氟丁定的代谢进行研究，氟丁汀是一种放射性示踪剂，可通过PET成像α4beta 2烟碱型乙酰胆碱受体
3. Gallium-68 and scandium-44 labelled radiotracers based on curcumin structure linked to bifunctional chelators: Synthesis and characterization of potential PET radiotracers [J] . Journal of Inorganic Biochemistry: An Interdisciplinary Journal . 2020,第期

机译：镓-68和Scandium-44基于姜黄素结构的无抗离子机构与双官能螯合剂连接：潜在的宠物放射体机构的合成和表征
4. Characterization of PET Radiotracers Through LC-MS/MS Measurement of the Radiotracer and Accompanying ~(13)CCarrier [C] . Umesha Shetty, Cheryl Morse, Yi Zhang, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2010

机译：通过LC-MS / MS测量的抗毒反射器和伴随的宠物放射体制物的表征，并伴随〜（13）C载体
5. Development of a system for real-time measurements of metabolite transport in plants using short-lived positron-emitting radiotracers. [D] . Kiser, Matthew R. 2008

机译：开发了一种使用短寿命正电子发射放射性示踪剂实时测量植物体内代谢产物的系统。
6. Characterization of fast-decaying PET radiotracers solely through LC-MS/MS of constituent radioactive and carrier isotopologues [O] . H Umesha Shetty, Cheryl L Morse, Yi Zhang, 2013

机译：仅通过LC-MS / MS对组成型放射性同位素和载流子同位素同位素进行快速衰减PET示踪剂表征
7. Characterization of fast-decaying PET radiotracers solely through LC-MS/MS of constituent radioactive and carrier isotopologues [O] . H Umesha Shetty, Cheryl L Morse, Yi Zhang, 2013

机译：仅通过LC-MS / MS对组成型放射性同位素和载流子同位素同位素进行快速衰减PET示踪剂表征

Characterization of PET Radiotracers Through LC-MS/MS Measurement of the Radiotracer and Accompanying ~(13)CCarrier

摘要

著录项

相似文献

相关主题

期刊订阅